Reisa A. Sperling

NIA‐AA Research Framework: Toward a biological definition of Alzheimer's disease

2018 · Alzheimer s & Dementia

In 2011, the National Institute on Aging and Alzheimer's Association created separate diagnostic recommendations for the preclinical, mild cognitive impairment, and dementia stages of Alzheimer's disease. Scientific progress in the interim led to an initiative …

Regional beta‐amyloid and tau deposition: Results from the Framingham Heart Study

2021 · Alzheimer s & Dementia

Abstract Background The Framingham Heart Study (FHS), a three‐generation community‐based cohort studying cardiovascular disease across the adult lifespan, has expanded to include positron emission tomography (PET) of beta‐amyloid (Aβ) and tau. Our aim is to …