Thomas G. P. Grünewald

Teacher-student collaborated multiple instance learning for pan-cancer PDL1 expression prediction from histopathology slides

2023 · bioRxiv (Cold Spring Harbor Laboratory)

ABSTRACT Programmed cell death ligand 1 (PDL1), as an important biomarker, is quantified by immunohistochemistry with few established histopathological patterns. Deep learning aids in histopathological assessment, yet heterogeneity and lacking spatially resolved annotations challenge precise …