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Researcher profile

George Davey Smith

2 papers in the PaperMetrix corpus

Publications

Papers by this author

  1. The MR-Base platform supports systematic causal inference across the human phenome

    2018 · eLife

    Results from genome-wide association studies (GWAS) can be used to infer causal relationships between phenotypes, using a strategy known as 2-sample Mendelian randomization (2SMR) and bypassing the need for individual-level data. However, 2SMR methods are …

  2. Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

    2015 · International Journal of Epidemiology

    BACKGROUND: The number of Mendelian randomization analyses including large numbers of genetic variants is rapidly increasing. This is due to the proliferation of genome-wide association studies, and the desire to obtain more precise estimates of …