Elyssia S. Gallagher

Designing a Comparative Proteomics Experiment: Retention-time Alignment and Imputation Algorithms Affect Statistical Comparisons Between Samples

2025 · ChemRxiv

Comparative proteomics experiments reveal biomarkers by using statistical tests to determine proteins expressed with higher abundance in one sample versus another. However, comparative experiments can be complicated by variability from all aspects of proteomics workflows. …